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The Pancreas

 

The pancreas forms part of the digestive and endocrine systems

 

The pancreas is a gland, about six inches long, located in the abdomen.

It is shaped like a flat pear and is surrounded by the stomach, small intestine, liver, spleen and gallbladder.

The wide end of the pancreas on the right side of the body is called the head.

The middle sections are the neck and body.

The thin end of the pancreas on the left side of the body is called the tail.

 

The pancreas is both an exocrine gland and endocrine gland and has two main functions – digestion and blood sugar regulation.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Pancreas as an Exocrine Gland

Exocrine glands have ducts - and they secrete onto a surface: examples of exocrine glands are: sebaceous and sweat glands in the skin and salivary glands in the mouth

 

Exocrine cells (acinar cells)) of the pancreas produce enzymes that help with digestion. When food enters the stomach, these cells release the pancreatic enzymes into a system of small ducts that lead to the main pancreatic duct. The pancreatic duct runs the length of the pancreas and carries pancreatic enzymes and other secretions, collectively called pancreatic juice.

 

The main pancreatic duct connects with the common bile duct, which carries bile from the gallbladder, and together they connect with the duodenum at a point called the ampulla of Vater. Here, bile and pancreatic enzymes enter the duodenum to aid in the digestion of fats, carbohydrates and proteins.

 

Pancreas as an Endocrine Gland

Endocrine glands do not have ducts. Their secretions (hormones) are secreted into the bloodstream. Because of this, the hormones can act over long distances, and reach any organ in the body to co-ordinate activity. Often there is a specific 'target' organ that the hormone acts on. 

 

The endocrine cells of the pancreas produce hormones, which are responsible for blood sugar regulation.

Hormones are substances that control or regulate specific functions in the body. They are usually made in one part of the body and carried through the blood to take action on another part of the body.

 

The two main pancreatic hormones are insulin and glucagon. Islet cells are endocrine cells within the pancreas that produce and secrete insulin and glucagon into the bloodstream. Insulin lowers blood sugar levels while glucagon raises blood sugar levels. Together, these two main hormones work to maintain the proper level of sugar in the blood.

 

Images courtesy of Dream Designs  at FreeDigitalPhotos.net

Image by  "Blausen gallery 2014". Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018762. - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=28909220

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